2,3,4,6-Tetra-O-Benzyl-D-Glucopyranose; 2,3,4,6-Tetra-O-Benzyl-α-D-Glucopyranose; Tetra-O-Benzyl-D-Glucopyranose; 2,3,4,6-Tetrakis-O-(phenylmethyl)-D-Glucopyranose cas 4132-28-9 / 6564-72-3 is a white to offwhite powder or crystalline solid. Insoluble in water,slightly soluble in dioxane and soluble in toluene etc.
Specification
Appearance White to offwhite powder or crystalline solid
Assay (HPLC), % ≥98
Melt point, ℃ 145~151
Specific Rotation [α], ° 15.5~22(C=1,CHCl3)
Loss of dry, % ≤1.0
Ash (residue on ignition), % ≤0.1
Heavy metal, ppm ≤10
As, ppm ≤1
Application
Uses: This product is an important derivant of D-glucopyranose, it is used for pharmaceutical intermediates and used in biochemical reactions and other chemical reactions.
As a pharmaceutical intermediate, for example, used in synthetize derivants of 3-position glycosylation for anti-Alzheimer disease, synthetize carbohydrate complexes of sulfate/ phosphate and glycoside derivatives of indolopyrrolocarbazole for treatment cancer, synthetize compounds of perfluoroalkyl-containing sugar radicals for diagnosis of cancer, synthetize Voglibose, ertugliflozin, nojirimycin and its derivants, glucose ester of glycyl-propionic acids for cure diabetes, and synthetize other pharmaceuticals such as polysaccharide, glycosylations derivatives with benzotriazole/ nitrophenyl and phospholipid-saccharide conjugates for treatment sepsis, meningitis, AIDS, osteoporosis, osteitis deformans or Paget’s diease etc.
Used in prepare 1-halogenation glucopyranose and synthesis other derivatives of 1- C-alkyl or glycosides -α-d-glucopyranosides, and so on. Moreover, the compound of 2,3,4,6-tetra-O-benzyl-1-C-vinyl-α-D-glucopyranose conjugate with 15-crown-5 ether is a novel chiral phase-transfer catalysts.
Storage: Maintain in cool, dry container.
Package: 10kg/drum or as customer require.