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  • Product Details
  • SDS
  • TDS
  • Reference COA

Where to Buy D-panthenol or Dexpanthenol 98% 75% cosmetic or pharmaceutical grade USP from China? TNJ Chemical, China leading D-panthenol factory suppliers offering best price. To buy D-panthenol from us makes you feel easy in business. If you want to inquire D-panthenol price or find reputed suppliers, please feel free to contact sales@tnjchem.com

 

Specification

Assay, % min.                            98-102
Water, % max.                           1.00
Specific optical rotation, °            +29-31.5
Limit of aminopropanol, % max.  1.00
Residue on ignition. % max.        0.10
Refractive index(20℃)                1.495-1.502

Heavy metals, ppm max.            20.00   

 

Application

In pharmaceuticals, cosmetics and personal-care products, panthenol is a moisturizer and humectant, used in ointments, lotions, shampoos, nasal sprays, eye drops, lozenges, and cleaning solutions for contact lenses.

In ointments it is used for the treatment of sunburns, mild burns, minor skin injuries and disorders (in concentrations of up to 2–5%). It improves hydration, reduces itching and inflammation of the skin, improves skin elasticity, and accelerates epidermal wounds' rate of healing. For this purpose, it is sometimes combined with allantoin.

In cosemtics,it is a humectant,emollient and moisturizer.It binds to hair follicles readily and is a frequent component of shampoos and hair conditioners(in concentrations of 0.1-1%),it coats the hair and seals its surface,lubricating follicles and making strands appear shiny.
In food and feed filed, as nutrition supplement and enhancer,promote the metabolism of protin,fat,sugar,keep the skin and mucous mermbrane, improbe hair gloss,enhance immunity,prevent the happening of the disease.

Packaging

15kg per plastic or as customer required;.

7.5mt-8mt per 20ft container

Material Safety Data Sheet MSDS of D-panthenol 98% CAS 81-13-0

Section 1: Chemical Product and Company Identification

Product Name: D-panthenol

CAS#: 81-13-0

CI#: Not available.

Chemical Formula: C9H19NO4

 

Contact Information:
Hefei TNJ Chemical Industry Co.,Ltd.
D1508 Xincheng Business Center Tel : (0086) 551 5418695
Qianshan Road, Hefei Fax: (0086) 551 5418697
230004Anhui Email: info@tnjchem.com
China Site: www.tnjchem.com

Section 2: Composition and Information on Ingredients
Composition:
Name                                CAS #                                 by Weight %
D-panthenol                      81-13-0                                      98
Toxicological Data on Ingredients: Not applicable.

Section 3: Hazards Identification
EMERGENCY OVERVIEW
Hygroscopic (absorbs moisture from the air).

Potential Health Effects Eye: May cause mild eye irritation. 

Skin: May cause mild skin irritation. 

Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

Inhalation: May cause respiratory tract irritation.

Chronic: No information found.


Section 4: First Aid Measures
Eyes:
In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively

Section 5: Fire and Explosion Data

General Information:

As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.

Extinguishing Media: 

Use water spray, dry chemical, carbon dioxide, or appropriate foam.


Section 6: Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.

Section 7: Handling and Storage
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse.
Storage:
Keep container closed when not in ues. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Store protected from moisture.

This product has the characteristic of crystallization, it may accelerate at low temperature, but thethere is no specific experiment to prove how much temperature will crystallize


Section 8: Exposure Controls/Personal Protection

Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 81-13-0:
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be whenever workplace conditions warrant respirator use.

Section 9: Physical and Chemical Properties
Physical State: Viscous liquid
Color: clear, colorless
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 118-120 deg C @ 0.02 mmHg
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: 140-161 deg C
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: freely soluble
Specific Gravity/Density: 1.200
Molecular Formula: C9H19NO4
Molecular Weight: 205.26

Section 10: Stability and Reactivity Data

Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions. Heating over 70C can cause racemization to DL-Panthenol, CAS = 16485-10-2.
Conditions to Avoid: Moisture, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11: Toxicological Information
RTECS#:
CAS# 81-13-0: ES4316000
LD50/LC50:
CAS# 81-13-0: Draize test, rabbit, eye: 500 ug Mild; Draize test,
rabbit, skin: 500 mg/4H Mild; Oral, mouse: LD50 = 15 gm/kg.
Carcinogenicity:
D-Panthenol -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are more toxic.
Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations
Waste Disposal:
Waste disposed

Section 14: Transport Information
DOT Classification: Not a DOT controlled material..
Identification: : Not applicable.
Special Provisions for Transport: Not available.

Section 15: Other Regulatory Information
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 81-13-0: 0
Canada
CAS# 81-13-0 is listed on Canada's DSL List.
CAS# 81-13-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 81-13-0 is listed on the TSCA inventory.

Section 16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 10/12/2018

Updated: 10/12/2022

 

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchant ability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall we be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if we has been advised of the possibility of such damages.

 

Technical Data Sheet TDS of D-panthenol/Dexpanthenol 98% CAS 81-13-0


Basic information

Chemical name     D-Panthenol

Formula    C9H19NO4

Synonyms   Dexpanthenol;Provitamin B

CAS.No.    81-13-0

EINECS No.   201-327-3

Chemical structure

Molecular weight   205.25

HS Code   2936240000


Physical properties

Appearance   Transparent viscous liquid, with a special smell, has a bitter taste.

Density,g/cm3   1.2

Boiling point,C    118-120

Refractive Index   1.495-1.502

Solubility    Soluble in water,ethanol,methanol,ropylene glycol,soluble in chloroform & ethyl ether, glycerin

Specification

Assay, %

98.0-102.0

Idengtification of Blue vitriol

Dark blue

Idengtification of IR trichloride

Purplish red

Residue on ignition, %

≤0.10

Related substances (Aminopropanol) , %

0.1.00

The specific rotation

29.0-31.5

Refractivity  (20C)

1.495-1.502

Moisture, %

≤1.0



Application

In pharmaceuticals, cosmetics and personal-care products, panthenol is a moisturizer and humectant, used in ointments,

lotions, shampoos, nasal sprays, eye drops, lozenges, and cleaning solutions for contact lenses.

 

In ointments, it is used for the treatment of sunburns, mild burns, minor skin injuries and disorders (in concentrations of up to 2 –5%). It improves hydration, reduces itching and inflammation of the skin, improves skin elasticity, and accelerates epidermal wounds' rate of healing. For this purpose, it is sometimes combined with allantoin.


In cosemtics, it is a humectant,emollient and moisturizer. It binds to hair follicles readily and is a frequent component of shampoos and hair conditioners(in concentrations of 0.1-1%),it coats the hair and seals its surface,lubricating follicles and making strands appear shiny.

In food and feed filed, as nutrition supplement and enhancer,promote the metabolism of protin,fat,sugar,keep the skin and mucous mermbrane, improbe hair gloss,enhance immunity,prevent the happening of the disease.

Package

98%: 20kg per plastic drum, 9.6mt per 20’ft with pallets wrapped


Safety on transportation

It belongs to common goods, always refer to MSDS.


Storage and handling

Keep tightyl closed, store in a cool dry place, sealed under less than 25C, shelf life is 2 years.

Please refer to the Materials Safety Data Sheet (MSDS) for the handling methods.

The information above is believed to be accurate and represents the best information currently available to us.However, In no event shall we be liable for any claims, losses, or damages of any third party resulting from its use. 

Issue Date: 1st, 02,2019 BY Hefei TNJ Chemical Industry Co.,Ltd.


Product name  D-Panthenol 98%

CAS. No.   81-13-0

M.F.   C9H19NO4

N.W.   3,000.00kg

G.W.   3,150.00kg

Batch No.   240604F061

Package   20.00kg/drum

MFG date   Jun. 04, 2024

Analysis date   Jun. 04, 2024

Retest date   Jun. 03, 2026

 

Items

Specification

Results

Appearance

Clear, viscous hygroscopic liquid. 

Some crystallization may occur on standing

Conforms

 

Solubility

Freely soluble in  water, in alcohol, in methanol, and in

propylene glycol; soluble in  chloroform and in  ether; slightly

soluble in glycerin; practically insoluble inheptane .

 

Conforms

 

 

Identification

A : Infrared absorption  < 197F>:  Conform to  USP2021

Conforms

B : The  Sample solution : a deep blue  color develops

Conforms

C : The  Sample solution: a purplish red color develops

Conforms

Assay (anhydrous basis),  %

98.00  ~  102.00

99.60

Water determination ,  %

≤1.00

0.15

Specific optical rotation , 。

+ 29.00  ~  + 31.50

+ 30.70

Limit of aminopropanol,  %

≤1.00

0.59

R esidue on ignition ,  %

≤0.10

0.06

R efractive index(20C)

1.495  ~  1.502

1.497

Heavy metals  (Pb), ppm

≤20.00

Conforms

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