Imidazole, CAS 288-32-4, with the molecular formula of c3h4n2, is an organic compound, a kind of diazole, and a five membered aromatic heterocyclic compound containing two meta nitrogen atoms in the molecular structure. The unshared electron pair of the nitrogen atom at the 1-position in the imidazole ring participates in the cyclic conjugation, and the electron density of the nitrogen atom decreases, making the hydrogen on the nitrogen atom easily leave in the form of hydrogen ions.
Imidazole is acidic and basic, and can form salts with strong bases. The chemical properties of imidazole can be summarized as the synthesis of pyridine and pyrrole. These two structural units play an important role in the catalysis of lipid hydrolysis by histidine as acyl transfer reagent in the enzyme. Imidazole derivatives exist in biological organisms and are more important than imidazole itself in scientific research and industrial production, such as DNA and hemoglobin.
Application area
Imidazole can be used as curing agent of epoxy resin, which can improve the mechanical properties of products such as bending, stretching and compression, improve the electrical properties of insulation, and improve the chemical properties of chemical agents. It is widely used in computers and electrical appliances; Used as a rust inhibitor for copper in printed circuit boards and integrated circuits;
It is used as medical raw material for manufacturing antifungal agents, antimycotics, hypoglycemic therapeutic agents, artificial plasma, trichomonal therapeutic agents, bronchial asthma therapeutic agents, anti macular agents, etc; It is used as pesticide raw material, synergist of boric acid preparation, preparation of insecticide and fungicide; In addition, imidazole is also used as raw material of urea formaldehyde resin curing agent, photographic medicine, adhesive, coating, rubber curing agent, antistatic agent, etc; Organic synthesis intermediates.
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