Brief introduction of DL-Dithiothreitol CAS 3483-12-3
Chemical name: DL-Dithiothreitol
CAS No.：3483-12-3
Synonyms: DL-1,4-Dithiothreitol
Molecular Formula: C4H10O2S2
Molecuar Weight: 154.25
EINECS: 222-468-7
Properties of DL-Dithiothreitol CAS 3483-12-3
DL-Dithiothreitol is a commonly used reducing agent, also called dimercaptothreitol (DTT). It has a strong reducibility, and its reducibility is largely due to its oxidation state of the six-membered ring (containing disulfide). Bond) conformational stability. The reducing power is affected by the pH value of the Chemicalbook, and it can only play a reducing effect when the pH value is greater than 7. This is because only the deprotonated thiolate anions (-S–) are reactive, while mercaptans (-SH) do not; and the pKa of sulfhydryl groups is generally ~8.3.
Specification of DL-Dithiothreitol CAS 3483-12-3
Item |
Standard |
Appearance |
White powder |
Assay, % |
≥98.0 |
Water,% |
≤0.5 |
Boiling point, ℃ |
41-44 |
Application of DL-Dithiothreitol CAS 3483-12-3
DL-Dithiothreitol is a small molecule organic reducing agent with a chemical formula of C4H10O2S2. It is mainly used in the field of biotechnology as a protein lysis reagent. At present, the most widely used Chemicalbook synthesis method for dithiothreitol uses threitol as a raw material, first oxidize with potassium permanganate, and then obtain a thio intermediate under the action of thioacetic acid, and finally hydrolyze the thio intermediate The body obtains dithiothreitol.
Packing, Delivery and Storage of DL-Dithiothreitol CAS 3483-12-3
Package: 25kg /bag or fiber drum, or as per customer request.
Storage conditions: store in a cool and dry place.
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