General overview of Furazolidone CAS 67-45-8

Furazolidone is a nitrofuran antibiotic that can be used to treat gastrointestinal diseases such as dysentery, enteritis, and gastric ulcer caused by bacteria and protozoa. Furazolidone is a broad-spectrum antibacterial drug, which has an inhibitory effect on common gram-negative and positive bacteria. The Ministry of Agriculture of the People's Republic of China lists furazolidone as a banned drug and must not be detected in animal food. The FDA also banned the use of nitrofurans (including furazolidone) in animal foods in 2002. The State Food and Drug Administration issued an announcement on February 15, 2019. Due to serious adverse reactions, it decided to stop the production, sales and use of furazolidone compound preparations in my country from now on, and the listed drugs will be recalled by manufacturers before the end of March 2019 . The furazolidone single preparation was not affected, bifurazolidone.

Furazolidone powder (CAS 67-45-8) exists in yellow crystalline powder. Furazolidone is a nitrofuran antibacterial agent and is used in human and veterinary medicine. Furazolidone is believed to work by crosslinking of DNA.

Specification
Description                       Yellow crystal powder
Identification                    Positive
Acidity                              4.5~7.0
Loss on drying                  ≤0.5%
Residue on ignition           ≤0.1%
Assay                               97.0%~103.0%
Nitrofurfural diacetate       ≤1.0%

Application

Use in humans
In humans it has been used to treat diarrhoea and enteritis caused by bacteria or protozoan infections. It has been used to treat traveler's diarrhoea, cholera and bacteremic salmonellosis. Use in treating Helicobacter pylori infections has also been proposed. Furazolidone is also used for giardiasis (due to Giardia lamblia), though it is not a first line treatment.
Use in animals
As a veterinary medicine, furazolidone has been used with some success to treat salmonids for Myxobolus cerebralis infections. It has also been used in aquaculture.
Use in laboratory
It is used to differentiate micrococci and staphylococci.

Packaging
25kg/fiber drum