HPMC Hydroxypropyl methyl cellulose CAS 9004-65-3 is a semisynthetic, inert, viscoelastic polymer used as an ophthalmic lubricant, as well as an excipient and controlled-delivery component in oral medicaments, found in a variety of commercial products. As a food additive, hypromellose is an emulsifier, thickening and suspending agent, and an alternative to animal gelatin.

Properties

1) Appearance: HPMC is a nonionic cellulose ether, white grayish-white powder or granule,odorless and flavorless, soluble in cold water, glacial acetic acid, ethanol, methanol and propylene glycol, slightly soluble in acetone depending on the degree of substitutions, practically insoluble in hot water, ethylene glycol and toluene. HPMC is dissolved in a mixture of 10% methanol and 90% methylene chloride to form colloidal solutions.
2) The solution of HPMC has surface activity, high transparency, and stable performance. When heated at certain temperature, the solution becomes cloudy or forms flocculent gel. However, the solution becomes clear again after cooling. Different types of HPMC have different gelation temperatures. The solubility varies with the viscosity. The lower the viscosity, the higher solubility it has. The different types of HPMC are different in some properties and their solubility in water is not affected by pH.
3) Particle sizes: 100% pass rate in 80 mesh.
4) Apparent density: 0.25-0.70 g/mL (usually about 0.5 g/mL),specific density 1.26-1.31mL.
5) Color change temperature:190-200°C; Carbonization temperature:280-300°C.
6) Surface tension:42-56 dyn/cm (2% aqueous solution).
7) The higher methoxy content in HPMC, the lower gelation temperature, and the higher solubility in water and surface activity.

8) HPMC has some other characteristics, for example, thickening property, pH stability, retention of water, excellent film-forming property, good disperse and adhesion ability

Specification for Phama Grade HPMC

Item               Viscosity (CPS, 2%Brookfield)                      Usage            (2%

E5                             4-5.5                                Suitable for plant capsule, coating
E6                             5.6-7.0                             Suitable for plant coating
E8                             7.1-9.0                             Suitable for plant coating
E10                           9.1-12.0                           Suitable for plant coating
E15                           12.1-18.0                         Suitable for plant coating
E30                           24-36                               Suitable for adhesive
E50                           40-60                               Suitable for adhesive
E70                           61-80                               Suitable for adhesive
E100                         91-120                             Suitable for adhesive
E4M                          3000-5000                        Suitable for sustained-control release preparations
K100                         91-120                             Suitable for adhesive
K4M                          3000-5000                        Suitable for sustained-control release preparations

K100M                      80000-120000                   Suitable for sustained-control release preparations

Specification for Industrial Grade HPMC

Item                  Viscosity (CPS, 2%Brookfield) ) Usage                             

TNJ-400                    400                                  Self-leveling
TNJ-4000                  4000                                Crack Filler
TNJ-10000                10000                              Crack Filler
TNJ-20000                20000                              Cement mortar & Crack Filler
TNJ-30000                30000                              Cement mortar, Crack Filler, External wall insulation & Ceramic Extrusion
TNJ-35000                35000                              Cement mortar
TNJ-45000                45000                              Cement mortar, External wall insulation & Ceramic Extrusion
TNJ-55000                55000                              Tile adhesive, External wall insulation & Gypsum-based plaster

TNJ-65000                65000                              Tile adhesive & External wall insulation

Application

There are many fields of application for hypromellose, including:

- Tile adhesives
- Cement renders
- Gypsum products
- Pharmaceutical
- Paints & coatings
- Food
- Cosmetics
- Detergents & cleaners
- Eye drops
- Contact lenses

Packing

Pharma grade:     25kg/fiber drum, 9mt/20''container

Industrial grade:   25kg/bag, 14mt/20''container