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Sodium Ethoxide
Sodium Ethoxide CAS 141-52-6

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  • Product Details

Sodium ethoxide (CAS 141-52-6) is a white to yellowish powder that dissolves in polar solvents such as ethanol. It is commonly used as a strong base. Sodium ethoxide solution is reddish brown viscous liquid with its alkaline stronger than NaOH.


Instead the material is typically prepared in a solution with ethanol. It is commercially available and as a solution in ethanol. It is easily prepared in the laboratory by treating sodium metal with absolute ethanol (2 C2H5OH +2 Na -- 2 C2H5ONa + H2). An alternative, cheaper route involves the reaction of sodium hydroxide with anhydrous ethanol. This reaction suffers from incomplete conversion to the alkoxide, but for less stringent applications, full conversion is unimportant. The salt product may be purified by precipitation in a solution of anhydrous acetone.


Sodium ethoxide solid gradually turns dark on storage in dry air because of oxidation.[5] In moist air, it hydrolyzes rapidly to sodium hydroxide. The conversion is not obvious and typical samples of NaOEt are contaminated with NaOH.

 

Specification of Sodium ethoxide

Sodium ethoxide liquid

Appearance            Reddish brown viscous liquid
Assay                    18%-21%
Free alkali              0.5% max

Sodium ethoxide solid

Appearance             Light yellow powder or particle
Assay                     99.0% min
Free alkali               1.0% max

Na2CO                   0.5% max


Application of Sodium ethoxide

Sodium ethoxide is commonly used in the Claisen condensation and malonic ester synthesis. Sodium ethoxide may either deprotonate the a-position of an ester molecule, forming an enolate, or the ester molecule may undergo a nucleophilic substitution called transesterification. If the starting material is an ethyl ester, trans-esterification is irrelevant since the product is identical to the starting material. In practice, the alcohol/alkoxide solvating mixture must match the alkoxy components of the reacting esters to minimize the number of different products.
Many alkoxides are prepared by salt metathesis from sodium ethoxide.

1. Ethoxylate agent,as well as a coagulant and reductant for organic synthesis,pharmaceuticals and pesticides synthesis;

2. Pharmaceutical products used sodium ethoxide are: phenobarbital, butazodine, primidone,methyldopa,tetracaine hydrochloride, eprazinone,aminopterin,pyrimethamine,horse ampicillin etc.

 

Packing

Liquid: 180kg/drum,80drums/20”container

Solid:   80kg/barrel (4 bags/barrel, 25kg/bag), 80drums/20"container

 

Storage
It should be storaged in cool and dry warehouse. It should be kept away from flame, heat resource, 
antioxidant, acids and storaged and transported isolatedly. 
Light handling and discharge.Keep packing complete.

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