CAS Nr.: 77-52-1
EINECS: 201-034-0
Molecular Formula: C30H48O3
Molecular Weight: 456.7
Description
Ursolic Acid, a naturally occurring triterpenoid, has been noted to demonstrate anti-angiogenic and anti-proliferative. Mechanistic studies suggest that this compound down-regulates MMP-2 and uPA expression in cells
via inhibition of Akt, JNK, mammalian target of Rapamycin phosphorylation, and levels of NFB protein in the nucleus.Other experiments have shown that Ursolic Acid may improve blood glucose, glucose tolerance, insulin tolerance,
glycosylated hemoglobin, and plasma leptin levels in diabetic murine models. Additionally, this agent displays a capacity to induce cell cycle arrest and apoptosis through activation of p53 pathway and Bax protein, as well as down-regulation of Bcl-2.
Physical Information
Physical State: yellow or greenish yellow powder.
Solubility: Soluble in ethanol (5 mg/ml warm), DMSO (>25 mg/ml warm), and DMF. Insoluble in water.Storage: Store at -20℃.
Melting Point: 285-288째 C
Density: 1.10 g/cm3 (Predicted)
Refractive Index: n20D 1.56 (Predicted)
Application
1. Applied in food field, as raw materials of tea is easy to reduce phlegm;
2. Applied in pharmaceutical field, may be it will become a new anti cancer drug with low toxic;3. Applied in cosmetic field, it can invigorate blood circulation and remove beverage
Packing
25kg/drum,or as per customer's requirement
Storage & Transport
Stored in cool and airy place; away from fire and heat; handle with care; no breakage, avoid leakage
This is classified as a Common Good for transport.
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